Name | Calcitonin (salmon) |
Synonyms | tz-ct Salcitonin Salcatonin Salmon Calcium Thyrocalcitonin salmoncalcitonini Calcitonin salmon Salmon calcitonin CalcitoninAcetate Calcitonin (salmon) Calcitonin (salmon I) thyrocalcitonin salmon salmoncalcitonin-(i-32) Salmon Calcitonin acetate Salmon Calcitonin Acetate CALCITONIN SALMON 250 UG H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2 (Disulfide bond) |
CAS | 47931-85-1 |
EINECS | 256-342-8 |
InChI | InChI=1/C145H240N44O48S2/c1-65(2)45-86(175-139(232)110(70(11)12)183-136(229)99-63-239-238-62-79(148)117(210)178-96(59-191)134(227)174-92(52-104(151)202)131(224)172-90(49-69(9)10)129(222)180-98(61-193)135(228)187-114(74(16)197)142(235)181-99)118(211)158-55-106(204)162-80(25-18-20-40-146)120(213)169-89(48-68(7)8)128(221)179-97(60-192)133(226)167-83(34-37-102(149)200)122(215)165-85(36-39-109(207)208)123(216)171-88(47-67(5)6)127(220)173-91(51-77-54-156-64-161-77)130(223)164-81(26-19-21-41-147)121(214)170-87(46-66(3)4)126(219)166-84(35-38-103(150)201)125(218)186-113(73(15)196)141(234)177-94(50-76-30-32-78(199)33-31-76)143(236)189-44-24-29-101(189)137(230)168-82(27-22-42-157-145(154)155)124(217)185-112(72(14)195)140(233)176-93(53-105(152)203)132(225)184-111(71(13)194)138(231)160-56-107(205)163-95(58-190)119(212)159-57-108(206)182-115(75(17)198)144(237)188-43-23-28-100(188)116(153)209/h30-33,54,64-75,79-101,110-115,190-199H,18-29,34-53,55-63,146-148H2,1-17H3,(H2,149,200)(H2,150,201)(H2,151,202)(H2,152,203)(H2,153,209)(H,156,161)(H,158,211)(H,159,212)(H,160,231)(H,162,204)(H,163,205)(H,164,223)(H,165,215)(H,166,219)(H,167,226)(H,168,230)(H,169,213)(H,170,214)(H,171,216)(H,172,224)(H,173,220)(H,174,227)(H,175,232)(H,176,233)(H,177,234)(H,178,210)(H,179,221)(H,180,222)(H,181,235)(H,182,206)(H,183,229)(H,184,225)(H,185,217)(H,186,218)(H,187,228)(H,207,208)(H4,154,155,157) |
InChIKey | IYTKRMFJECGBRF-LXQLIYPUSA-N |
Molecular Formula | C145H240N44O48S2 |
Molar Mass | 3431.85 |
Density | 1.54±0.1 g/cm3(Predicted) |
Melting Point | >222oC (dec.) |
Water Solubility | Soluble in water at 1mg/ml |
Solubility | 0.05 M acetic acid: 1mg/mL, clear, colorless |
Appearance | powder |
Color | White to Off-White |
Merck | 13,1642 |
Storage Condition | −20°C |
Refractive Index | 1.676 |
MDL | MFCD00133859 |
Use | Hypocalcetin (Hypocalcemic hormone) is produced by the parafollicular C cells or by the gills of invertebrates (nonmammalian vertebrates). The decrease of calcium and phosphorus in blood inhibits the absorption of osteoblasts (osteoblasts) and osteocytes cells. |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
RTECS | EV8000000 |
FLUKA BRAND F CODES | 3-10 |
HS Code | 2937190000 |
Reference Show more | Protective effects of Jinggu Bushen granule on osteoporosis rats induced by dexamethasone [J]. Chinese patent medicine, 2016, 29 (6):1221-1225. |
[Ingredients]
The main component of this product is combined into salmon calcitonin, and its chemical name is force:
(1, 7-disulfide) cysteinyl-seryl-asparaginyl-leucyl-seryl-tachyyl-cysteinyl-valyl-leucyl-glycyl
lysyl-leucyl-leucyl-leucyl-leucyl-leucyl-leucyl-leucyl-leucyl-leucyl-leucyl-leucyl-leucyl-leucyl-leucyl-leucyl-leucyl-prolyl-leucyl-leucyl-asparagine-leucyl-leucyl-leucyl-leucyl-leucyl-leucyl-leucyl-leucyl-Thenyl-Prolinamide
Molecular weight: 3431.89
[properties] the contents of this product are colorless or almost colorless clear liquids.
[seat suitability]
1. Osteoporosis:
2. Bone pain with osteolysis and/or osteopenia.
3.Paget's disease (osteitis deforming), especially in patients with the following conditions:
4. Hypercalcemia and high calcium crisis caused by the following conditions:
5. Neurodystrophy (painful neurodystrophy or Sudeck's disease): It is caused by different causes and causes, such as posttraumatic osteoporosis, sympathetic dystrophy, shoulder-arm syndrome, burning pain caused by peripheral nerve injury, and neurodystrophy caused by drugs.